Encounter: Edgar and Alan Frog, a pair of monster hunters whose encyclopedic knowledge of how to defeat the various types of monsters is exceeded only by their hatred of them. Could be more useful during the actual fight, though.
Encounter: Mr. Measles, lawful evil plague-cleric somehow skilled enough to give inanimate objects the measles, although how exactly he intends for that to let him rule the world is unclear. Affected characters take d4 levels of Exhaustion and will spend the next 4d4 days itchy, Exhausted, and contagious unless affected by a Cure Disease spell or similar. Affected objects work poorly or slowly at the DM’s discretion, and can infect creatures but not other objects.
Encounter: Griff Slaughter, a human fighter that got tired of adventuring and beat up the staff of a Hyundai dealership until they appointed him sales/general manager